Sunday 14 December 2014

Slipped strand mispairing


Slipped strand mispairing (SSM) is a mutation process which occurs during DNA replication. It involves denaturation and displacement of the DNA strands, resulting in mispairing of the complementary bases. Slipped strand mispairing is one explanation for the origin and evolution of repetitive DNA sequences. Slipped strand mispairing has also been shown to function as a phase variation mechanism in certain bacteria

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